HI-PLUS

HI-PLUS is a Germany-wide, cluster-randomized parallel-arm controlled trial funded within the German Innovation Fund (Grant #01NVF19029; registered as DRKS00031997). A cluster is defined as a cardiological practice that cooperates with general practitioners. A total of 1332 heart failure patients with reduced left ventricular ejection fraction (LVEF ≤40%) will be recruited in 74 cardiological practices. 

The practices will be randomised into two groups. In the control group, HF patients are treated according to usual care.  In the intervention group, 5 elements are added: a) care program derived from a positively evaluated trial; b) eHealth telemonitoring and documentation platform; c) portable telemedical devices (scales, BP monitor, ECG) as needed; d) care implementation supported through a specifically trained non-medical assistant qualified in HF (HI‑MFA); e) enhanced communication between cardiologist and general practitioner via HI-MFA and eHealth platform.

The HI-PLUS trial is investigating, whether implementation of an evidence-based structured care program improves quality of life among HF patients compared to usual care.