RedAres
The aim of the RedAres study is to optimise the treatment and prescription rate of medication for uncomplicated urinary tract infections (UTI). The participating practices were randomised into two groups and provided anonymised prescription data at different times. They received feedback as well as information material and handouts. Both the practices and their patients benefited from this during and after the end of the study.
The project began on 1 September 2019 and the study ended on 31 December 2022. The current pathogen and resistance situation in uncomplicated UTI was initially surveyed and presented by the Robert Koch Institute in five regions of Germany (sub-project a).
From April 2021 to March 2022, a twelve-month randomised, controlled study with a complex intervention on prescription behaviour in uncomplicated UTIs was conducted in a total of 128 GP practices (sub-project b).
The accompanying process analysis of technical feasibility and acceptance enables a subsequent direct transfer to standard care (sub-project c).
REDARES was coordinated by the Institute of General Practice of the University of Würzburg. The ICE-B performed data management and statistical analysis for sub-project b. Further information on the project can be found at
https://www.allgemeinmedizin.uni-wuerzburg.de/forschung/redares/
Publications
Gágyor, I., Greser, A., Heuschmann, P., Rücker, V., Maun, A., Bleidorn, J., Heintze, C., Jede, F., Eckmanns, T., Klingeberg, A., Mentzel, A., & Schmiemann, G. (2021). REDuction of Antibiotic RESistance (REDARES) in urinary tract infections using treatments according to national clinical guidelines: study protocol for a pragmatic randomized controlled trial with a multimodal intervention in primary care. In BMC Infectious Diseases (Vol. 21, Issue 1). Springer Science and Business Media LLC. https://doi.org/10.1186/s12879-021-06660-0
Schmiemann, G., Greser, A., Maun, A., Bleidorn, J., Schuster, A., Miljukov, O., Rücker, V., Klingeberg, A., Mentzel, A., Minin, V., Eckmanns, T., Heintze, C., Heuschmann, P., & Gágyor, I. (2023). Effects of a multimodal intervention in primary care to reduce second line antibiotic prescriptions for urinary tract infections in women: parallel, cluster randomised, controlled trial. In BMJ (p. e076305). BMJ. https://doi.org/10.1136/bmj-2023-076305
