Prof. Dr. Dr. Götz Gelbrich
Prof. Dr. Dr. Götz Gelbrich
Phone: | +49 931 / 201 46409 |
Fax: | +49 931 / 201 647310 |
E-Mail: | goetz.gelbrich@klinik.uni-wuerzburg.de |
short CV
since 2012 | Professor (W2) of biometry and deputy of the Institute of Clinical Epidemiology and Biometry, University of Würzburg |
2011 | Venia legendi for Medical Biometry and Epidemiology, University Leipzig |
2008 | 2nd doctoral degree (Dr. rer. med., summa cum laude), University of Leipzig |
since 2003 | senior biometrician of the German Competence Network Heart Failure |
1999-2012 | Biometrician at the Clinical Trial Centre Leipzig, University of Leipzig |
1995 | Doctoral Thesis Award, University of Greifswald |
1994 | 1st doctoral degree (Dr. rer. nat., summa cum laude) University of Greifswald |
1990-1999 | assistant at the Institute of Mathematics and Informatics, University of Greifswald |
1990 | mgr matematyki (with distinction), Warsaw University |
1985-1990 | diploma study of mathematics, Warsaw University |
Research interests
Biometry, clinical trials, study design, clinical epidemiology
.
Main Publications in recent years
- [ 2024 ]
- [ 2023 ]
- [ 2022 ]
- [ 2021 ]
- [ 2020 ]
- [ 2019 ]
- [ 2018 ]
- [ 2017 ]
- [ 2016 ]
- [ 2015 ]
- [ 2014 ]
- [ 2013 ]
- [ 2012 ]
2024[ to top ]
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Population data-based federated machine learning improves automated echocardiographic quantification of cardiac structure and function: the Automatisierte Vermessung der Echokardiographie project. Eur Heart J Digit Health. 2024;5(1):77-88..
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Heart rate variability, interoceptive accuracy and functional connectivity in middle-aged and older patients with depression. J Psychiatr Res. 2024;170:122-9..
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Determinants and reference values of the 6-min walk distance in the general population-results of the population-based STAAB cohort study. Clin Res Cardiol. 2024;..
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Prognostic Utility of Pericardial Effusion in the General Population: Findings From the STAAB Cohort Study. Journal of the American Heart Association [Internet]. 2024;:e035549. Available from: https://www.ahajournals.org/doi/abs/10.1161/JAHA.124.035549.
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2023[ to top ]
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Intensive heart rhythm monitoring to decrease ischemic stroke and systemic embolism-the Find-AF 2 study-rationale and design. Am Heart J. 2023;265:66-7..
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Heart rate-corrected systolic ejection time: population-based reference values and differential prognostic utility in acute heart failure. Eur Heart J Imaging Methods Pract. 2023;1(2):qyad020..
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Deep phenotyping as a contribution to personalized depression therapy: the GEParD and DaCFail protocols. J Neural Transm (Vienna). 2023;130(5):707-22..
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The Population Comparison Index: An Intuitive Measure to Calibrate the Extent of Impairments in Patient Cohorts in Relation to Healthy and Diseased Populations. Int J Environ Res Public Health. 2023;20(3)..
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Generalised anxiety and panic symptoms in the German National Cohort (NAKO). World J Biol Psychiatry. 2023;24(10):881-96..
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The assessment of cognitive function in the German National Cohort (NAKO) - Associations of demographics and psychiatric symptoms with cognitive test performance. World J Biol Psychiatry. 2023;24(10):909-23..
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2022[ to top ]
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The assessment of cognitive function in the German National Cohort (NAKO) - Associations of demographics and psychiatric symptoms with cognitive test performance. World J Biol Psychiatry. 2022;:1-15..
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Mild autonomous cortisol secretion portends similar cardiac compromise as overt endogenous Cushings syndrome. European Heart Journal - Cardiovascular Imaging [Internet]. 2022;23(Supplement_1). Available from: https://doi.org/10.1093/ehjci/jeab289.178.
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Endogenous Cushings syndrome is associated with impaired myocardial work efficiency. European Heart Journal - Cardiovascular Imaging [Internet]. 2022;23(Supplement_1). Available from: https://doi.org/10.1093/ehjci/jeab289.166.
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Generalised anxiety and panic symptoms in the German National Cohort (NAKO). World J Biol Psychiatry. 2022;:1-16..
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2021[ to top ]
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Left Ventricular Remodeling and Myocardial Work: Results From the Population-Based STAAB Cohort Study. Front Cardiovasc Med. 2021;8:669335..
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Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP). Infection. 2021;49(6):1277-8..
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Impact of cardiovascular risk factors on myocardial work—insights from the STAAB cohort study. Journal of Human Hypertension [Internet]. 2021;36(3):235-4. Available from: https://doi.org/10.1038/s41371-021-00509-4.
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Seroprävalenz von COVID-19 und psychosoziale Auswirkungen in der Allgemeinbevölkerung: Ergebnisse des STAAB-COVID-One Programms. Das Gesundheitswesen. 2021;83(12):965-7..
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Is PFS the Right Endpoint to Assess Outcome of Maintenance Studies in Multiple Myeloma? Results of a Patient Survey Highlight Quality-of-Life As an Equally Important Outcome Measure. Blood [Internet]. 2021;138:836. Available from: https://www.sciencedirect.com/science/article/pii/S000649712102824X.
- [ DOI ]
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Prevalence and determinants of the precursor stages of heart failure: results from the population-based STAAB cohort study. European Journal of Preventive Cardiology [Internet]. 2021;28(9):924-3. Available from: https://doi.org/10.1177/2047487320922636.
- [ DOI ]
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DIPS (Dystonia Image-based Programming of Stimulation: a prospective, randomized, double-blind crossover trial). Neurological Research and Practice [Internet]. 2021;3(1):65. Available from: https://doi.org/10.1186/s42466-021-00165-6.
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Functional versus morphological assessment of vascular age in patients with coronary heart disease. Scientific Reports [Internet]. 2021;11(1):18164. Available from: https://doi.org/10.1038/s41598-021-96998-x.
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2020[ to top ]
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Myocardial work - correlation patterns and reference values from the population-based STAAB cohort study. PLoS One. 2020;15(10):e0239684..
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Brain Natriuretic Peptide and Discovery of Atrial Fibrillation After Stroke. Stroke [Internet]. 2020;51(2):395-401. Available from: https://www.ahajournals.org/doi/abs/10.1161/STROKEAHA.119.026496.
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Comparison of three methods to estimate dental age in children. Clin Oral Investig. 2020;24(7):2469-75..
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Consumption of Lactobacillus reuteri-containing lozenges improves periodontal health in navy sailors at sea: A randomized controlled trial. Journal of Periodontology [Internet]. 2020;91(10):1328-3. Available from: https://aap.onlinelibrary.wiley.com/doi/abs/10.1002/JPER.19-0393.
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2019[ to top ]
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Physicians’ lifestyle advice on primary and secondary cardiovascular disease prevention in Germany: A comparison between the STAAB cohort study and the German subset of EUROASPIRE IV. Eur J Prev Cardiol. 2019;:2047487319838218..
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Economic evaluation of prolonged and enhanced ECG Holter monitoring in acute ischemic stroke patients. Current Medical Research and Opinion [Internet]. 2019;35(11):1859-66. Available from: https://doi.org/10.1080/03007995.2019.1646000.
- [ DOI ]
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Segment-specific association of carotid-intima-media thickness with cardiovascular risk factors - findings from the STAAB cohort study. BMC Cardiovasc Disord. 2019;19(1):84..
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Variations in cardiovascular risk factors in people with and without migration background in Germany – Results from the STAAB cohort study. International Journal of Cardiology [Internet]. 2019;286:186-9. Available from: https://www.sciencedirect.com/science/article/pii/S0167527318341305.
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Long-term outcome of patients with relapsed/refractory B-cell non-Hodgkin lymphoma treated with blinatumomab. Blood Advances [Internet]. 2019;3(16):2491-8. Available from: https://doi.org/10.1182/bloodadvances.2019000025.
- [ DOI ]
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Speckle tracking derived reference values of myocardial deformation and impact of cardiovascular risk factors - Results from the population-based STAAB cohort study. PLoS One. 2019;14(9):e0221888..
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Impact of Patient Beliefs on Blood Pressure Control in the General Population: Findings from the Population-Based STAAB Cohort Study. Int J Hypertens. 2019;2019:9385397..
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2018[ to top ]
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Public funding for medical research in relation to the burden of disease caused by cardiovascular diseases and neoplasms in Germany. Clin Res Cardiol. 2018;107(9):737-44..
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Amount or intensity? Potential targets of exercise interventions in patients with heart failure with preserved ejection fraction. ESC Heart Failure [Internet]. 2018;5(1):53-62. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1002/ehf2.12227.
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Secondary Prevention in Younger vs. Older Coronary Heart Disease Patients-Insights from the German Subset of the EUROASPIRE IV Survey. Int J Behav Med. 2018;25(3):283-9..
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Abstract WP201: Stroke Patients With Atrial Fibrillation Detected by 72 hour- versus Prolonged ECG-monitoring. Stroke [Internet]. 2018;49(Suppl_1):AWP201-AWP201. Available from: https://www.ahajournals.org/doi/abs/10.1161/str.49.suppl_1.WP201.
- [ DOI ]
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Impact of acquisition and interpretation on total inter-observer variability in echocardiography: results from the quality assurance program of the STAAB cohort study. The International Journal of Cardiovascular Imaging [Internet]. 2018;34(7):1057-65. Available from: https://doi.org/10.1007/s10554-018-1315-3.
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High-grade glioma associated immunosuppression does not prevent immune responses induced by therapeutic vaccines in combination with T(reg) depletion. Cancer Immunol Immunother. 2018;67(10):1545-58..
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2017[ to top ]
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Holter-electrocardiogram-monitoring in patients with acute ischaemic stroke (Find-AF(RANDOMISED)): an open-label randomised controlled trial. Lancet Neurol. 2017;16(4):282-90..
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Control of cardiovascular risk factors and its determinants in the general population- findings from the STAAB cohort study. BMC Cardiovasc Disord. 2017;17(1):276..
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2016[ to top ]
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Characteristics and Course of Heart Failure Stages A-B and Determinants of Progression - design and rationale of the STAAB cohort study. Eur J Prev Cardiol. 2016;24(5):468-79..
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Auditory Monitoring in Vestibular Schwannoma Surgery: Intraoperative Development and Outcome. World Neurosurg. 2016;96:444-53..
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Non-Motor Symptoms of Essential Tremor Are Independent of Tremor Severity and Have an Impact on Quality of Life. Tremor Other Hyperkinet Mov (N Y). 2016;6:361..
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Effect of Escitalopram on All-Cause Mortality and Hospitalization in Patients With Heart Failure and Depression: The MOOD-HF Randomized Clinical Trial. Jama. 2016;315(24):2683-93..
- [ DOI ]
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Tolerability and Feasibility of Beta-Blocker Titration in HFpEF Versus HFrEF: Insights From the CIBIS-ELD Trial. JACC Heart Fail. 2016;4(2):140-9..
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Interactions of donor sources and media influence the histo-morphological quality of full-thickness skin models. Biotechnol J. 2016;11(10):1352-61..
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[Assessment of subjective physical well-being in heart failure : Validation of the FEW16 questionnaire]. Herz. 2016;42(2):200-8..
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When Does Hearing Loss Occur in Vestibular Schwannoma Surgery? Importance of Auditory Brainstem Response Changes in Early Postoperative Phase. World Neurosurg. 2016;95:91-8..
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2015[ to top ]
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Combining wrist age and third molars in forensic age estimation: how to calculate the joint age estimate and its error rate in age diagnostics*. Annals of Human Biology [Internet]. 2015;42(4):389-96. Available from: https://doi.org/10.3109/03014460.2015.1046487.
- [ DOI ]
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Depressive symptoms in heart failure: Independent prognostic factor or marker of functional status?. J Psychosom Res. 2015;78(6):569-72..
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Influence of different aetiologies on clinical course and outcome in patients with dilated cardiomyopathy. Eur J Clin Invest. 2015;45(9):906-17..
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Comparative potential of the 2-item versus the 9-item patient health questionnaire to predict death or rehospitalization in heart failure. Circ Heart Fail. 2015;8(3):464-72..
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Verschiedene Gesichter der Altersschätzung: Methodische Betrachtungen aus der Sicht einzelner Disziplinen. Rechtsmedizin. 2015;25:7-11..
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Reverse epidemiology in different stages of heart failure. Int J Cardiol. 2015;184:216-24..
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Poor self-rated health predicts mortality in patients with stable chronic heart failure. Eur J Cardiovasc Nurs. 2015;15(7):504-12..
- [ DOI ]
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Natriuretic peptides for the detection of paroxysmal atrial fibrillation. Open Heart [Internet]. 2015;2(1):e000182. Available from: http://openheart.bmj.com/content/2/1/e000182.abstract.
- [ DOI ]
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Improvement of Ventricular-Arterial Coupling in Elderly Patients with Heart Failure After Beta Blocker Therapy: Results from the CIBIS-ELD Trial. Cardiovasc Drugs Ther. 2015;29(3):287-94..
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Cost-effectiveness and cost-utility of a structured collaborative disease management in the Interdisciplinary Network for Heart Failure (INH) study. Clin Res Cardiol. 2015;104(4):304-9..
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Effects of exercise training on different quality of life dimensions in heart failure with preserved ejection fraction: the Ex-DHF-P trial. Eur J Prev Cardiol. 2015;22(5):582-93..
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Nurse-coordinated collaborative disease management improves the quality of guideline-recommended heart failure therapy, patient-reported outcomes, and left ventricular remodelling. Eur J Heart Fail. 2015;17(4):442-52..
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Galectin-3 in patients with heart failure with preserved ejection fraction: results from the Aldo-DHF trial. Eur J Heart Fail. 2015;17(2):214-23..
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2014[ to top ]
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Finding atrial fibrillation in stroke patients: Randomized evaluation of enhanced and prolonged Holter monitoring--Find-AF(RANDOMISED) --rationale and design. Am Heart J. 2014;168(4):438-445.e1..
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Associations of methylarginines and homoarginine with diastolic dysfunction and cardiovascular risk factors in patients with preserved left ventricular ejection fraction. J Card Fail. 2014;20(12):923-30..
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Longitudinal assessments of erythropoietin-stimulating agent responsiveness and the association with specific clinical outcomes in dialysis patients. Nephron Clin Pract. 2014;128(1-2):147-52..
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Regional differences among female patients with heart failure from the Cardiac Insufficiency BIsoprolol Study in ELDerly (CIBIS-ELD). Cardiol J. 2014;21(3):265-72..
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A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy. Eur Heart J. 2014;35(16):1069-77..
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Effects of structured heart failure disease management on mortality and morbidity depend on patients’ mood: results from the Interdisciplinary Network for Heart Failure Study. Eur J Heart Fail. 2014;16(10):1133-41..
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Heart rate following short-term beta-blocker titration predicts all-cause mortality in elderly chronic heart failure patients: insights from the CIBIS-ELD trial. Eur J Heart Fail. 2014;16(8):907-14..
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Auditory brainstem implants in neurofibromatosis Type 2: is open speech perception feasible?. J Neurosurg. 2014;120(2):546-58..
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2013[ to top ]
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Effect of Spironolactone on Diastolic Function and Exercise Capacity in Patients With Heart Failure With Preserved Ejection Fraction: The Aldo-DHF Randomized Controlled Trial. JAMA [Internet]. 2013;309(8):781-9. Available from: https://doi.org/10.1001/jama.2013.905.
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Valvular manifestations of human immunodeficiency virus infection--results from the prospective, multicenter HIV-HEART study. J Cardiovasc Med (Hagerstown). 2013;14(10):733-9..
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Self-rated health predicts adverse events during β-blocker treatment: the CIBIS-ELD randomised trial analysis. Int J Cardiol. 2013;163(1):87-92..
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Prevalence of cardiovascular diseases in HIV-infected outpatients: results from a prospective, multicenter cohort study. Clin Res Cardiol. 2013;102(3):203-13..
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Generic and disease-specific health-related quality of life in patients with chronic systolic heart failure: impact of depression. Clin Res Cardiol. 2013;102(4):269-78..
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Incidence rates and predictors of major and minor depression in patients with heart failure. Int J Cardiol. 2013;167(2):502-7..
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Differential interaction of clinical characteristics with key functional parameters in heart failure with preserved ejection fraction--results of the Aldo-DHF trial. Int J Cardiol. 2013;169(6):408-17..
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Age-dependent yield of screening for undetected atrial fibrillation in stroke patients: the Find-AF study. J Neurol. 2013;260(8):2042-5..
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Systemic treatment of metastatic uveal melanoma: review of literature and future perspectives. Cancer Med. 2013;2(5):674-86..
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2012[ to top ]
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Effect of beta blockade on natriuretic peptides and copeptin in elderly patients with heart failure and preserved or reduced ejection fraction: results from the CIBIS-ELD trial. Clin Biochem. 2012;45(1-2):117-22..
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Implementation of pharmacotherapy guidelines in heart failure: experience from the German Competence Network Heart Failure. Clin Res Cardiol. 2012;101(4):263-72..
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Impact of the β1-adrenoceptor Arg389Gly polymorphism on heart-rate responses to bisoprolol and carvedilol in heart-failure patients. Clin Pharmacol Ther. 2012;92(1):21-8..
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Telemedicine in heart failure: pre-specified and exploratory subgroup analyses from the TIM-HF trial. Int J Cardiol. 2012;161(3):143-50..
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Sinus rhythm versus atrial fibrillation in elderly patients with chronic heart failure--insight from the Cardiac Insufficiency Bisoprolol Study in Elderly. Int J Cardiol. 2012;161(3):160-5..
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Is target dose the treatment target? Uptitrating beta-blockers for heart failure in the elderly. Int J Cardiol. 2012;155(1):160-6..
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Functional orthosis in shoulder joint subluxation after ischaemic brain stroke to avoid post-hemiplegic shoulder-hand syndrome: a randomized clinical trial. Clin Rehabil. 2012;26(9):807-16..
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Serum aldosterone and its relationship to left ventricular structure and geometry in patients with preserved left ventricular ejection fraction. Eur Heart J. 2012;33(2):203-12..
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Mode of action and effects of standardized collaborative disease management on mortality and morbidity in patients with systolic heart failure: the Interdisciplinary Network for Heart Failure (INH) study. Circ Heart Fail. 2012;5(1):25-3..
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Beta blockers therapy is associated with improved left ventricular systolic function and sustained exercise capacity in elderly patients with heart failure. CIBIS-ELD sub-study. Aging Clin Exp Res. 2012;24(6):675-81..
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Gender-specific predictors of early mortality after coronary artery bypass graft surgery. Clin Res Cardiol. 2012;101(9):745-51..
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Natriuretic peptides for the detection of paroxysmal atrial fibrillation in patients with cerebral ischemia--the Find-AF study. PLoS One. 2012;7(4):e34351..
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