Deutsch Intern
Chair of orthopedic

Research

Our research is focused on the cell biology of mesenchymal stromal cells (MSC) of different tissue origins. MSC populations have been described in various tissues. Based on their ability to give rise to different cell types (e.g. adipocytes, chondrocytes and osteoblasts) and their secretory potential they are of great interest in Regenerative Medicine. Our projects aim to decipher interactions of MSC with their environment, both in physiology and pathophysiology. Increasing the knowledge on such interactions as well as mechanisms of adaptation in course of degenerative diseases, will facilitate the development of new therapeutic approaches.


Currently, we are working on following topics:


New therapeutic strategies for reconstruction of bone defects with optimized RIA-derived autologous grafts and bone substitute materials - RIABONE

Sebastian Häusner, Bianca Schlierf, Theresa Kreuzahler, Marietta Herrmann

Collaborators: Torsten Blunk (Würzburg), Aleksandra Jaukovic, Dusko Spasovski, Petar S. Milosavljević  (Belgrad), OSARTIS GmbH

 

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Regulation of bone marrow stromal cells (BMSC) and regenerative processes by inflammatory factors

Drenka Trivanovic, Magdalena Stöckl, Noah Volkmann, Bianca Schlierf, Theresa Kreuzahler, Marietta Herrmann
 

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The extracellular matrix environment of bone marrow stromal cells

Ana Rita Pereira, Drenka Trivanovic, Bianca Schlierf, Theresa Kreuzahler, Marietta Herrmann
 

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Completed Projects:


Identification and metabolic profiling of bone marrow adipose tissue progenitors

Annika Schiminski, Christoph Kölbl, Bianca Schlierf, Marietta Herrmann, Drenka Trivanovic
 

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