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20th Dutch-German Joint Meeting of the Molecular Cardiology Working Groups

16th – 18th March 2023 Würzburg

 

Thursday, 16th March, 2023

 

12:00 - 12:45 Poster Set-up

 

12:45 - 13:00 Welcome and Organizational Issues

 

13:00 – 14:30 Session 1: Cardio-Immunology

Chair 1: Gustavo Ramos, Würzburg

Chair 2: Anke Smits, Leiden

 

Talk 1 Cholesterol efflux pathways control T cell aging and atherosclerosis - Marit Westerterp, Groningen

Talk 2 Clonal hematopoiesis of indeterminate potential (CHIP) – an acquired genetic cardiovascular risk factor in search of a mechanism - Ingo Hilgendorf, Freiburg

Talk 3 The role of lipid binding GPCRs in cardiac and vascular inflammation - Sabine Steffens, München

Talk 4 Inflammation in the heart: adaptive traits and therapeutic opportunities – Kai Wollert, Hannover

                         

14:30 - 16:30 Poster Session I and Coffee

 

 

16:30 – 18:00 Session 2: Mitochondrial and Metabolic Impact on Cardiovascular Disease

 

Chair 1: Stefan Frantz, Würzburg

Chair 2: Bianca Brundel, Amsterdam

 

Talk 1 Mitochondrial targets in myocardial ischemia/reperfusion injury - Judith Haendeler, Düsseldorf

Talk 2 SGLT2 inhibitors directly affect the cardiac Na+-interactome: is SGLT2 needed for SGLT2 inhibitors to protect the heart? –Coert Zuurbier, Amsterdam

Talk 3 Increased myocardial ketone body oxidation underlies the salutary effects of SGLT2-inhibitors in heart failure - Daan Westenbrink, Groningen

Talk 4 Redox signaling in vascular injury - Flavia Rezende, Frankfurt


 

Friday, 17th March, 2023

 

9:00 - 10:30 Session 3: Cardiomyopathies

Chair 1: Friederike Cuello, Hamburg

Chair 2: Miranda Nabben, Maastricht

 

Talk 1 Genetic and molecular insights in inherited cardiomyopathies - Brenda Gerull, Würzburg

Talk 2 In vitro and in vivo models to study the molecular pathogenesis of arrhythmogenic cardiomyopathy - Martina Calore, Maastricht

Talk 3 Investigating treatment strategies in a PLN-R14del mouse cardiomyopathy model - Herman Silljé, Groningen

Talk 4 Molecular mechanisms underlying RBM20 cardiomyopathy - Maarten van den Hoogenhof, Heidelberg

 

10:30 - 11:00 Coffee Break

 

11:00 - 12:30 Session 4: Systems Biology in Cardiovascular Disease

Chair 1: Esther Creemers, Amsterdam

Chair 2: Benjamin Meder, Heidelberg

 

Talk 1 A data-driven strategy to dissect molecular remodeling in cardiac disease - Alicia Lundby, Kopenhagen

Talk 2 Spatial-omics approaches to study heart diseases - Berta Cillero-Pastor, Maastricht

Talk 3 Deciphering the mechanism of RBM20 mislocalization in dilated cardiomyopathy- Julia Kornienko, Heidelberg

Talk 4 Spatial multi-omic map of human myocardial infarction. – Christoph Kuppe, Aachen

 

12:30 - 14:30 Poster Session II and Lunch

 

14:30 - 15:15 Keynote Lecture 1 

Chair: Kristina Lorenz, Würzburg 

Modelling cardiotoxicity, drug responses and disease in human iPSC-derived CM - Christine Mummery, Leiden

15:15 - 15:45 Coffee Break

15:45 - 17:15 Session 5: Young Investigator Award Session

Judge/Chair 1: Sabine Klaassen, Berlin

Judge/Chair 2: Blanche Schroen, Maastricht

Judge/Chair 3: Christiane Vettel, Mannheim

Judge/Chair 4: Leon de Windt, Maastricht

Judge/Chair 5: Larissa Fabritz, Hamburg

Judge/Chair 6: Niels Voigt, Göttingen

 

 

Talk 1 Rocco Caliandro, Amsterdam

Talk 2 Anna Lischke, Karlsruhe

Talk 3 Felix Trogisch, Heidelberg

Talk 4 Philipp Konrad, Heidelberg

 


 

Saturday, 18th March, 2023

 

9:00 - 10:30 Session 6: Cardio-Oncology

Chair 1: Monika Stoll, Münster

 

 

Talk 1 Cancer - a major cardiac comorbidity - Lorenz Lehmann, Heidelberg

Talk 2 tba- Wouter Meijers, Rotterdam

Talk 3 Reverse cardio-oncology: shared mechanisms and pathophysiology- Joseph Pierre Aboumsallem, Rotterdam

Talk 4 Is heart failure a risk factor for cancer? - Johannes Backs, Heidelberg

 

10:30 - 11:00 Coffee Break

11:00-11:45 Keynote Lecture 2

Chair: Albert Sickmann, Dortmund

Platelets as targets in cardiovascular diseases - Bernhard Nieswandt, Würzburg

 

11:45 - 12:30 Lunch Break

 

12:30 – 14:00 Session 7: Novel Strategies in Cardiovascular Research

Chair 1: Ferdinand le Noble, Karlsruhe

Chair 2: Laura Zelarayán, Göttingen

 

Talk 1 CRISPR/Cas9-mediated regulation of gene transcription - Eric Schoger, Göttingen

Talk 2 Therapeutic AAV gene transfer strategies - Oliver Müller, Kiel

Talk 3 Human iPSC-derived 3D vessel-on-chip to model vascular disease and beyond- Marc Vila Cuenca, Leiden

Talk 4 Single cell approaches to investigate cardiac pathophysiology - Monika Gladka, Amsterdam

 

14:00 YIA Winner and Poster Prize Announcement

 

14:30 Departure

 

Poster Judges:

Thomas Wieland

Rabea Hinkel

Susanne Lutz

Toon van Veen

Jörg Heineke

Ali El-Armouche

Joachim Altschmied

Anke Fender